Khoom taw qhia
IDRA-21yog benzothiadiazine-chav kawm compound uas muaj cov qauv heterocyclic tshwj xeeb uas hloov kho glutamate receptor kev ua rau cuam tshuam rau neural signaling. Kev tshawb fawb hauv vitro qhia nws lub peev xwm los txhim kho synaptic plasticity. Nws cov khoom siv tshuaj ruaj khov ua rau nws haum raws li cov cuab yeej tshawb fawb.
High Selectivity:Hom phiaj tshwj xeeb receptor subtypes.
Kev ruaj ntseg:Chemically ruaj khov ntawm chav tsev kub.
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Pnpe roq |
IDRA-21 |
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Lwm lub npe |
7-Chloro-3-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine-1,1-dioxide |
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CAS Nr. |
22503-72-6 |
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Cov mis mos molecular |
C8H9ClN2O2S |
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Molecular hnyav |
232.69 |
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Purity |
99% |
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Qhov tshwm sim |
Dawb rau tawm -dawb crystalline hmoov |
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Ntim |
1kg / hnab; 25kg / nruas |
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Daim ntawv thov |
chemical sim cov ntaub ntawv |
Mechanism of Action: Allosteric Modulation of AMPA Receptors
Lub zog zoo allosteric modulator (PAM) ntawm AMPA-hom glutamate receptors yog IDRA-21.
Mechanism ntawm Action:
IDRA-21 khi rau qhov chaw allosteric ntawm AMPA receptors, sib piv rau agonists ncaj qha. Los ntawm kev ua kom qeeb qeeb ntawm cov txheej txheem ntawm receptor desensitization thiab deactivation, nws txhim kho glutamate-mediated synaptic kis tau tus mob.
Cov txiaj ntsig tshawb fawb: IDRA-21 yog ib qho cuab yeej zoo tshaj plaws rau kev tshawb fawb ntev - lub sij hawm muaj zog (LTP) thiab synaptic plasticity vim tias nws muaj li kaum mus rau peb caug npaug ntau dua li Aniracetam thiab muaj lub neej ntev dua li ib nrab ntawm lub neej.
Rau txhua pawg ntawm Idra-21, TIANJIN YINAO muab cov lus qhia meejCertificate of Analysis (COA)los lav qhov rov ua dua ntawm koj qhov kev tshawb pom. Siv HPLC thiab HNMR tsom xam, peb ua tib zoo saib xyuas purity (Ntau dua lossis sib npaug li 99.5%) kom paub tseeb tias tsis muaj cov kuab tshuaj lom.
Kev Tshawb Fawb Txog Kev Tshawb Fawb
Zivkovic et al., "Idra-21Txhawb nqa qhov Induction ntawm Ntev-Lub Sijhawm Muaj Peev Xwm (LTP)" Phau ntawv Journal of Pharmacology thiab Kev Tshawb Fawb Kev Kho Mob.
Keeb kwm hauv Abstract:
Txawm tias muaj tsawg heev, Idra-21 tau pom nyob rau hauv ntau qhov kev sim los pab txhawb kev tsim lub sijhawm ntev (LTP) hauv hippocampal synapses.
Cov txiaj ntsig tseem ceeb:
Idra-21 tau pom tias txhim kho kev txawj ntse hauv nas thiab tsis yog- tib neeg primates. Ntxiv nrog rau kev txhim kho synaptic kis tau tus mob, nws kuj ua rau kom cov kev qhia ntawm lub hlwb-derived neurotrophic factor (BDNF), uas txhawb neuroplasticity thiab neuronal ciaj sia taus.
Muaj nuj nqi
1. Kev paub ntau ntxiv
2. Ua haujlwm kom raug
3. Ua kom lub cim xeeb luv luv
4. Muaj peev xwm kho tau tus mob schizophrenia
5. Muaj peev xwm kho tau los ntawm kev nyuaj siab
OEM & ODM
Daim ntawv thov
IDRA-21, raws li ib qho tseem ceeb ntawm cov cuab yeej tshawb fawb sib xyaw, ua kom pom cov txiaj ntsig ntawm daim ntawv thov dav thoob plaws ntau yam kev qhuab qhia vim nws cov yam ntxwv tshwj xeeb molecular. Hauv kev tshawb fawb tseem ceeb, nws ua haujlwm tsis yog rau kev tshawb xyuas cov txheej txheem kev paub txog molecular thiab ua cov organic synthesis nruab nrab (tshwj xeeb hauv heterocyclic compound synthesis), tab sis kuj yog cov qauv siv los txhawb txoj kev txhim kho analytical. Hauv kev tshawb fawb siv, IDRA-21 plays lub luag haujlwm tseem ceeb hauv kev siv biotechnology suav nrog kev txhim kho cov khoom siv thiab kev tsim qauv molecular. Ntawm qhov tseem ceeb, cov kev tshawb fawb sim tau qhia tias IDRA-21 optimizes neural signal kis tau tus mob, nthuav tawm lub peev xwm los tswj lub hlwb tseem ceeb - ib qho cuab yeej uas ua rau kev paub txog kev ua haujlwm thiab kev nco txog kev txhim kho.
Cov ntawv pov thawj
Cov qauv siab dua, kev tiv thaiv ntau dua
Tuam txhab
Tianjin Yinao Technology Co., Ltd. tau tsim nyob rau hauv 2017, nyob rau hauv lub nroog zam ntawm Tuam Tshoj - Tianjin. Muaj ib lub tuam txhab muaj kev sib koom ua ke tag nrho ntawm kev tsim khoom, kev muag khoom thiab kev pabcuam. Tsom ntsoov rau kev ua OEM, tshwj xeeb tshaj yog txhua yam tshuaj ntsiav, lub raj mis thiab lwm yam. Feem ntau xa tawm cov tshuaj thiab cov khoom noj khoom haus, cov khoom siv tshuaj thiab kev tsim lub cev los txhawb kev tshawb fawb txog kev ua neej thiab kev loj hlob, nrog rau kwv yees li ib puas txoj haujlwm tsim kev pabcuam.
Delivery & Shipping & Pob
International Express-- Fedex/DHL/UPS, huab cua shipping thiab hiav txwv shipping, ob-clearance kev cai.
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Ntim Cov Lus Qhia |
10g / Hnab, 1Kg / hnab / 25kg / Nruas, Raws li koj xav tau |
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Chaw nres nkoj |
Tuam Tshoj qhov chaw nres nkoj loj |
Vim li cas thiaj xaiv peb?
Q: Koj puas tuaj yeem tau txais tus qauv dawb?
A: Peb tuaj yeem muab cov qauv dawb rau koj, koj tsuas yog yuav tsum tau them tus nqi thauj khoom.
Q: Kuv tuaj yeem ntseeg koj li cas?
A: Peb tus tswv muaj ntau tshaj 20 xyoo ntawm kev paub hauv cov khoom siv tshuaj lom neeg thiab peb cov neeg ua haujlwm. Nws yog vim muaj kev ntseeg siab ntawm peb cov neeg siv khoom thiab cov neeg koom tes uas peb muaj peev xwm muaj nyob thiab txhim kho tau ntau xyoo. Peb lub zeem muag mus ib txhis yog 'Tau txais ntau yam khoom siv los ntawm cov neeg siv khoom los ntawm- kev yuav khoom zoo thiab kev pabcuam zoo tshaj plaws, thiab tsim kom muaj kev sib raug zoo ntawm cov neeg siv khoom ruaj khov thiab ruaj khov'!
Q: Koj tuaj yeem lav qhov zoo ntawm koj cov khoom li cas?
A: Tag nrho peb cov khoom ua raws li cov qauv kev sim hauv lub tebchaws thiab cov qauv thoob ntiaj teb. Yog tias koj xav tau, peb tuaj yeem muab cov ntawv pov thawj rau koj.
Q: Koj puas tuaj yeem siv cov neeg siv khoom- cov ntawv tshwj xeeb thiab ntim khoom?
A: Tau kawg, koj tuaj yeem muab peb cov ntawv teev npe thiab ntim khoom thiab peb yuav zoo siab ua raws li koj.assist koj. Yog tias muaj lwm yam koj xav tau, thov koj xav tiv tauj peb!
Q: Yuav ua li cas txog lub sij hawm xa khoom thiab txoj kev?
A: Peb feem ntau xa tuaj hauv 3-5 hnub ua haujlwm tom qab them nyiaj.
Peb tuaj yeem ua nkoj los ntawm hiav txwv, huab cua, lossis nthuav tawm. Kuj tseem tuaj yeem ua qhov rooj - mus rau - qhov rooj xa khoom.
Cim npe nrov: Idra-21, Tuam Tshoj Idra-21 Hoobkas
